Hosts made a great return to action with winning after the international break, securing a place in the next FA Cup with a 3-1 win over Brighton and are going into tonight's game with a good mode. Tottenham have now won 4 of their last 5 matches at their stadium, with an a1-0 loss to city rivals Chelsea the bad result in that streak. Good news for Tottenham fans as new midfielders Rodrigo Bentancur and Dejan Kulusevski both made impressive games off the bench in mentioned FA Cup game, and will surely be a good addition for the squad of Antonio Conte. 

Southampton lost only 1 of their last 8 competitive matches, that coming on the away but have conceded at least 2 goals in their last 6 away matches! They did a successful job in FA Cup against lower-tier Coventry on weekend but had to play 120 minutes and penalties lottery to go further in the competition. When it comes to team news, defender Lyanco is out of the squad for several months with a serious injury. Armando Broja is without training practice since the weekend. Nathan Tella and Alex McCarthy are still out for Saints. 

Tottenham have triumphed in their last 6 games at home against Southampton in all competitions and have scored at least 2 goals in the last 6 against them. The team of Antonio Conte will hunt here three points and fans want a reaction after losing versus city rivals Chelsea in the latest EPL game back in January. Having all information on the table, I think it's very realistic to expect a home win today, the odds are decent! Predicting 3-1 home win with Kane to score at least 2 goals!