Despite Leverkusen's stronger home performance this season, Monaco is currently in better form. However, Leverkusen's tactical setup thrives in stretched games where they can exploit teams in transition with their pace and guile. This may be a challenge in the two-legged knockout tie against Monaco, who will likely come to Germany looking to defend and force Leverkusen to beat them. Monaco's defensive strategy suggests they are not interested in controlling possession or space. They rank 9th in possession rate and 14th in expected threat allowed in Ligue 1, yet their defensive numbers remain solid as a whole, with few big scoring chances allowed. This could frustrate Leverkusen and force them to overcommit in the first leg, leaving gaps for Monaco to exploit behind their defense.Despite Monaco starting the game without much control of possession, they have demonstrated the sheer quality of their key players, who are fast starters on the road. Monaco has scored the opening goal in 9 of their 11 Ligue 1 away games this season and did so in two of their three UEL away group games. Therefore, it is a risk to predict that the first half will not be goalless, as Monaco could find a way to score early on. Leverkusen will be without key players Charles Aranguiz, Andrey Lunyov, and Patrik Schick, who are out with injuries. In their absence, Robert Andrich, Moussa Diaby, and Adam Hlozek are likely to start against Monaco. Goalkeeper Lukas Hradecky has kept five clean sheets this season, the same number of goals that Jeremie Frimpong has scored for Leverkusen, putting him second on the team with two fewer than Diaby. Monaco's Malang Sarr and Vanderson are out with injuries, but Wissam Ben Yedder is in form, scoring a brace against PSG and moving into second all-time in Ligue 1 scoring this century with 140 goals, behind only former Monaco striker Kylian Mbappe. Striker Kevin Volland may feature in the game, albeit from the bench, after scoring a hat-trick in Monaco's final UEL group fixture against Crvena Zvezda, helping them qualify for the knockout round playoffs.

尽管勒沃库森本赛季主场表现更强，但摩纳哥目前状态更好。然而，勒沃库森的战术设置在紧张的比赛中表现出色，他们可以利用他们的速度和诡计利用转换中的球队。这在对阵摩纳哥的两回合淘汰赛中可能是一个挑战，摩纳哥很可能会来到德国寻求防守并迫使勒沃库森击败他们。摩纳哥的防守策略表明他们对控制球权或空间不感兴趣。他们的控球率在法甲联赛中排名第 9 位，允许的预期威胁排名第 14 位，但他们的防守数据总体上保持稳定，几乎没有大的得分机会。这可能会让勒沃库森感到沮丧，并迫使他们在第一回合中过度投入，从而为摩纳哥队的防守留下空档。尽管摩纳哥队在比赛开始时并没有太多控球权，但他们已经证明了他们的关键球员的绝对素质，他们是快速的首发在路上。摩纳哥在 9 场比赛中打进了首球他们本赛季 11 场 Ligue 1 客场比赛，并且在他们的三场 UEL 客场小组赛中有两场。因此，预测上半场不会没有进球是有风险的，因为摩纳哥可能会早早找到进球的方法。勒沃库森将失去因伤缺阵的关键球员查尔斯·阿兰吉斯、安德烈·卢尼约夫和帕特里克·希克。在他们缺席的情况下，罗伯特·安德里奇、穆萨·迪亚比和亚当·赫洛泽克可能会在对阵摩纳哥的比赛中首发。守门员卢卡斯·赫拉德基本赛季保持了五场不失球，与杰雷米·弗林蓬为勒沃库森打进的进球数相同，比迪亚比少两球，位居全队第二。摩纳哥队的马朗萨尔和范德森因伤缺阵，但维萨姆本耶德尔状态良好，在对阵巴黎圣日耳曼的比赛中梅开二度，并以 140 个进球进入本世纪法甲历史第二，仅次于前摩纳哥前锋姆巴佩。前锋凯文·沃兰德在摩纳哥决赛上演帽子戏法后可能会出现在比赛中，尽管是替补席UEL 小组赛对阵 Crvena Zvezda，帮助他们晋级季后赛淘汰赛。